Mebendazole reduced the surviving fraction of cancer cells in a greater extent compared to ABZ and FBZ. Liver Flushing alone wouldnt kill, say, a fluke in your pancreas or spleen. Jane McLelland is an advocate of mebendazole and states in her book that mebendazole is a chemical compound that slows down fast cell division and works similarly to some chemotherapy drugs but without the same toxicity. Cancer is then able to do its damage by outnumbering and outliving normal cells. Mebendazole is an FDA approved antiparasitic agent with a well-established side effect and safety record and was effective in our animal models in dosing schedules that are documented as safe in humans. The mebendazole you can take for that infestation of pinworms will also disrupt microtubule formation (this disrupts cancer cell division) and stabilizes the p53 oncogene (halting cancer cell growth). … It is no longer available from any manufacturer in the U.S. No reason was given for the discontinuation. I have a wife, three kids, parents, and extended family that I love – plenty of reasons to keep fighting. I also believe it could be used periodically to “purge” the body of cancerous and pre-cancerous cells which have yet to gain cell mass through uncontrolled growth. The cost averages around 2-3 dollars for a compounded 100 mg. capsule. Hardik Patel. Off-label refers to the use of drugs for a purpose not intended by the pharmaceutical company. Only mebendazole has that honor. Scientists have long known how MBZ works to kill parasites, and as it turns out, cancer cells have something in common with parasites. The broad-spectrum of activity and safety of mebendazole remain, after 5 years of clinical experience, unique features of this anthelmintic. Mebendazole kills flukes of every kind, kills hydatid sand, is effective against ascaris, and is even proving effective in lung cancer, possibly because of its parasite killing ability. MBZ selectively targets the spindles of both, while leaving healthy cells untouched. Mebendazole (MBZ) showed a highly selective inhibitory effect at concentrations as low as <5 μM on the colon cancer cell lines, while sparing the normal, untransformed cell lines completely, indicating that in the clinical setting side-effects or by-stander effects should be minimal. Both the dose and length of treatment are determined by your personal physician. MBZ selectively targets the spindles of both, while leaving healthy cells untouched. Validation experiments were performed using human colon cancer cell lines HT29, HCT-8, and SW626 and non-malignant epithelial, renal, and hepatocyte … Of course, Fenben is stronger and of all from the chemical structure is best because it is in the middle of all these chemicals. He put an aggressive, late-stage cancer that had spread throughout his body into remission by taking a cocktail of drugs that included fenbendazole. Warmest regards, Studies using both cell cultures and mouse models demonstrated that mebendazole was effective in decreasing the growth of brain tumor cells. They don’t prescribe these drugs. The drugs of interest are mebendazole and fenbendazole. And cancer is beaten at every stage. He said, “probably because of money…all of these drugs are far off-patent and nobody is going to spend a gazillion dollars to repurpose them for cancer…..only to have generic competition the next day.”. Dr. Ben Williams is another amazing cancer success story. Mebendazole is available in the U.S through compounding pharmacies with a doctor’s prescription. Dr. Maxwell is Board Certified in Family Medicine, Integrative Medicine and Osteopathic Medicine. I like to be able to say what I am learning... My name is David Kent. It is interesting how similar all the anthelmintics are and where chemically are the differences. It stops the synthesis of their microtubules, in the same way as the cancer drug vinicristine. In the book, “How to Starve Cancer” by Jane McLelland, Jane steps through the metabolic attack she mounted on her cancer using off-label drugs. Notify me of follow-up comments by email. Present efforts to fight cancer involve attempting to isolate the cancer cells and selectively removing or poisoning them. Conventional chemotherapy and radiation are not selective enough to protect healthy cells, so “collateral damage” is often a major problem. Mebendazole was evaluated in cisplatin-resistant high grade serous stage 3C ovarian cancer patient derived xenograft (PDX) models: PDX-0003 (p53 null) and PDX-0030 (p53 positive), and on ovarian cancer cell lines: MES-OV (p53 R282W), ES2 (p53 S241F), A2780 (p53 wild type), SKOV3 parental (p53 null) and isogenic sublines, SKOV3 R273H p53 and SKOV3 R248W p53. Indeed, Mebendazole, alone or combined with chemo, has been shown to be effective against multiple forms of cancer cells, such as: adrenal cancer (Ref.1, Ref.2) colon cancer (Ref.1, Ref.2) brain cancer, medulloblastoma, glioblastoma (Ref.1, Ref.2, Ref.3, Ref.4) Mebendazole: From Pinworm Cure To Cancer Cure? The Benzimidazole-Based Anthelmintic Parbendazole: A Repurposed Drug Candidate That Synergizes with Gemcitabine in Pancreatic Cancer (Ref.) Dr. Maxwell, Just wondering what kind of dose I would need I have metastatic squamous cell carcinoma in lungs and ribs from head and neck primary hpv16+, Hello Kevin, So my question is… how bad do you want to live? Recently, it was discovered that mebendazole may be effective in treating cancer as well, in particular brain tumors. There is also some evidence that mebendazole can help to ‘starve’ a tumor by blocking the growth of blood vessels the tumor needs to supply oxygen and nutrients (Pantziarka et al., 2014). The data are summarised and discussed in relation to suggested mechanisms of action. While it kills cancer cells it poses no harm to the normal cells and has little or no side effects. You have entered an incorrect email address! The conclusion is that diet, vitamin supplementation, and fenbendazole dramatically reduced tumor growth in a lymphoma cell line. It is safe to use high doses of fenbendazole, because in the past patients used high doses of mebendazole, up to 2,000 to 3,000 mg for more than three weeks, when parasites were … That’s why mebendazole is different. I am glad to share this information with you. For a patient with metastatic cancer who is developing rapidly and many, he recommends taking 222mg of fenbendazole four times a day for three weeks, taking 222mg once or twice a day after the third week and resting for four days. Prayers Answered!!! It is fairly inexpensive, at about 2-3 dollars a pill. I currently take mebendazole with a prescription but supplement it with Vitamin E. I will explain later why I supplement with Vitamin E.  The COC protocol also includes Metformin, Doxycycline, and Atorvastatin. Hello, The purpose of this study was to conduct a controlled evaluation of mebendazole's therapeutic efficacy in cell culture and in vivo models of ovarian cancer. If there are too many errors in its DNA code, the cell will not be able to reproduce and the errors die within that cell. Disclaimer of Medical AdviceYou understand and acknowledge that all users of this website are responsible for their own medical care, treatment, and oversight. If you read Joe Tippen’s story, you can see he was very careful in this department. Methods. Please feel free to ask about any of our professional grade nutritional products, and our staff will be glad to assist you. Since this drug interferes with glucose metabolism, it can be effective for cancer therapy. My regimen is ever changing but a rotating regimen between the two drugs makes the most sense to me at this juncture. I have fired one oncologist and 3 surgeons. Dr. Maxwell, I was wondering what dosis you should take and how many times a year in order to PREVENT cancer. Clinical trials look at new ways to prevent, detect, or treat disease. But a growing number of integrative doctors were already aware of this, and had been using the medication “off-label” for several years with very good results! So mebendazole’s new use was discovered, as many treatments are, quite by accident. People are beating cancer at every stage. However, Medical Oncology Doctor said his blood result for Hemoglobin is getting lower & CEA, CA19.9 is not good. Most of us are familiar with this medication. Please keep me posted on your father’s progress. All of the content provided on the website, including text, treatments, dosages, outcomes, charts, profiles, graphics, photographs, images, advice, and messages, are for informational purposes only and DOES NOT CONSTITUTE THE PROVIDING OF MEDICAL ADVICE and is not intended to be a substitute for independent professional medical judgment, advice, diagnosis, or treatment. I take you back to Joe Tippen’s blog and several Facebook posts that I found on the Facebook group MyCancerStoryRocks to answer this question for myself. So at this point, we have two cases that partially attribute mebendazole to the defeat of two very different cancer types (I define defeat of cancer by long-term remission). I worked third shift, operating a huge machine called a Sig Packer. The answer is yes according to this PubMed article, https://www.ncbi.nlm.nih.gov/pubmed/1003277. P.O. But here’s the amazing news! You can see how close they are. Started taking Them over 4 years ago and my cancer has gone ..a link to my story http://www.abovetopsecret.com/forum/thread822776/pg1, Hello Shane, This has been my experience with patients as well. We started at 3 on and 4 off.. then went to 7 days on and 4 off. PS – I have found the content at cancertreatmentresearch.com to be excellent. They have a US branch too. Dr. Maxwell. I have had my blood drawn more times than I can count, a colonoscopy (not as bad as I thought it would be), and two CT scans … one of those scans with a tube up my butt. He defied all odds by putting a nasty brain tumor into remission with mebendazole and several other non-conventional drugs. Save my name, email, and website in this browser for the next time I comment. Joe is actively tracking success stories and has received scores of emails attributing his cocktail to their successful attack on cancer. Many years ago, she was told she had a few weeks to live and decided to take matters into her own hands and it made all the difference. The scientists were mystified. I am not a doctor and don’t recommend anyone take anything. This depends on the patient’s overall health including such things as other medicines being taken, age, and weight. Specially Niclosamide is known for its anti-cancer power independent of TP53 and can kill cancer cells when P53 is mutated and makes trouble …. The inspectors were quite good at recognizing, and grabbing, less-than-perfect cookies and removing them before they reached my trusty Sig Packer and me. While in pre-med at The University of Cincinnati, I was fortunate to have a job at Keebler here in Cincinnati (Fairfax), Ohio. This is only anecdotal and subjective evidence that fenbendazole is better but it is what I have to work with. By the way, I make no money off any of this, so take it or leave it. I am not a number. Thank you. Doctors have the legal ability to prescribe off-label drugs if they deem fit, including controlled substances. What do I do if I miss a dose? The metformin so useful for diabetes decreases insulin levels in the blood which has now been shown to slow down cancer and maximize survival. This is similar to how our immune system works to remove and destroy abnormal cells. Here is a short video animation of how spindles work: Here is a video of the microtubules, showing how they assemble and disassemble. * Mebendazole, or MBZ, is a similar compound and many researchers think it better than Fenbendazole against cancer. His complete recipe includes: A few other posts that you might find interesting regarding the differences. As metronidazole is a prescription here in the U.S., it would need to be prescribed by a physician who would need to see you in Dr. Maxwell, Hello Amin, This does not necessarily mean that one is more effective at killing cancer cells than the other. I have had 22 tumors removed from my body, from 3 different organs. The longer a shoestring is, the longer it can last when a few pieces break off. Our immune system quickly identifies and destroys these abnormal cells, as long as our immune system is in optimal shape. I am sorry to hear about all your father is going through. Reading through the wealth of knowledge online and within several books, I came across the use of off-label drugs to assist in the fight against all kinds of cancers. Off-label drugs can be over-the-counter or prescription drugs. Most scientists agree that this number is around 60 times. To ensure high quality service and diagnosis, kindly complete this form. Another article from Nature speaks to fenbendazole’s anti-cancer effects. Based on this, a cocktail of both drugs could be the answer. Interestingly, Johnson and Johnson still markets it throughout much of the world for the treatment of parasites, where it is widely available and inexpensive. They are also called microtubules. Therefore, mebendazole is a possible anti-cancer therapeutic with pre-clinical safety and efficacy and provides a promising opportunity for a clinical trial in patients with malignant gliomas. I am suffering Brain Tumor (Astrocytroma Grade 2, Size 5.7 X 3.6 X 3.4 cm)) and want to take Metronidazole Pil. But, the work underscores that the two drugs do operate differently. It keeps them from reproducing. On the chemical point of view please take a look at the chart below. Fax: (513) 741-7994. I have gone through the blog in which you mentioned the effectiveness of Metronidazole Pil in Cancer. A healthy bit of cynicism about the medical industry cannot hurt when you are trying to save your own life. Scientists have long known how MBZ works to kill parasites, and as it turns out, cancer cells have something in common with parasites. What an amazing, complex design! Taken under the tongue. This prevents the ability of the cells to divide. Surgery sometimes stimulates growth even more, resulting in a temporary relapse and regrowth. Many compounding pharmacies in the U.S can provide this medication. Write CSS OR LESS and hit save. The cells then die due to old age. Again, a PubMed article titled, “Comparative efficacies of ivermectin, febantel, fenbendazole, and mebendazole against helminth parasites of gray foxes.” This article is from 1986 but you can see how fenbendazole was more effective than mebendazole in this particular study. Mebendazole is a well known anti-helimintic and belongs to the benzimidazole group of medicines. While this study is old, 1976, you can see that these two drugs are behaving differently. © 2020 Ask Dr Maxwell Biopsy will be scheduled for the neck gland to see if it is cancer or not. Mebendazole is a drug used to treat infections with intestinal parasites and has a long track record of safety in humans. There is a balance. Mebendazole, a well-known anti-helminthic drug in wide clinical use, has anti-cancer properties that have been elucidated in a broad range of pre-clinical studies across a number of different cancer types. Expression of p53 and p21 You may be referring to metronidazole, a generic form of Flagyl. It was later found that this group of mice had been given mebendazole for pinworm. After all, we make millions of new cells daily, and a few are bound to be rejects. The Gamma E by Life Extension and Perfect E brand’s were recommended. Stephan provided the following graphic illustrating the structure of mebendazole, fenbendazole, and several other chemical compounds known to fight cancer. The associated drugs include albendazole, thiabendazole, riclabendazole, flubendazole, mebendazole and fenbendazole. 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Safety profile matter where you order it, a cocktail of drugs for a purpose not intended by Pharmaceutical! A healthy bit of practice to pronounce sorry to hear he is starting the Metronidazole protocol, as has. By their oncologist for taking off-label drugs without their doctor ’ s direction is old, 1976 you! We make millions of new cells daily, and metastases formation in vivo, heavily infested patients may be on. Of safety in humans 2A is short acting cytokine agent that acts as an immune modulator ( booster.! I initially thought both drugs would effectively be the answer the body interesting done. Using diet, exercise, drugs, and weight in this thing like..., Joe had been given weeks to live with docetaxel for prostate cancer treatment years for the of...