I read online to keep taking it throughout... I’ve been on Dhea to improve egg quality for over a year. Due to start 2nd round of ICIS at the end of April. Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. We will do another collection in Nov again, so probably won't do a transfer until next year because xmas gets in the way!! Any thoughts? I started taking DHEA mid/end Jan (from memory I think the clinic said to take it for 6 weeks prior to ivf) and got a natural bfp in March just before starting our ivf. Use of this site is subject to our terms of use and privacy policy. Apparently if you do convert it well (and agruably I do), DHEA is better than testosterone as your organs only take what they need with DHEA, whereas with testosterone apparently all organs get it equally, so some may get too much and others too little. Good to hear there have been no side effects. I did A LOT of research on it before asking my RE, and was still hesitant of taking it, but figured we had to try something after our previous cycle. Beyond age, the use of certain medications like insulin and corticosteroids can also cause DHEA levels to diminish. I don't know. I was almost 34. I didn't have any side effects but did follow instructions closely- feel free to dm me personally I highly recommend DHEA. I am taking Chinese herbs, DHEA, coQ10, l-arginine, and vitamin E in addition to the standard prenatal vitamin and fish oil. I stopped since I chose her to do my 2nd IVF round. They told me to stop taking the menopur and just continue with the decapatyl until the next blood test in 4 days time. I haven't noticed any side effects yet either X. fertilise) I have been taking dhea in the hope it helps to improve egg quality and numbers. After treatment, the women produced more eggs and a higher percentage of eggs were fertilized — … In turn, DHEA helps produce other hormones, including testosterone and estrogen. I took DHEA for 7 weeks before starting my IVF (in vitro fertilization) cycle and stopped when I achieved a positive pregnancy with a HPT. DHEA blood levels tend … Yea drop down to 25mg usually recommended for longer use daily. Anyone know when you should stop taking DHEA during IVF? Are you sure you want to delete your comment? My second and current doctor told me to immediately stop taking dhea. Are you sure you want to delete your discussion? Have you had any FETs yet? For women with DOR, the generally recommended DHEA dosage for female fertility purposes is 75 mg daily, which is split into three 25mg doses (to keep a stable supply in the body and avoid an upset stomach. Also, by the time of the 3rd collection, the geneticist said she would reduce my DH's sample down even further, as in our 2nd collection we got A LOT of double or triple fertilisation (7 out of 16 eggs). For inability to become pregnant within a year of trying to conceive (infertility): 75 mg of DHEA taken daily for 2-3 months before and during IVF treatment. I usually find I am better going through a stim cycle as I feel like I am actually doing something. Recent studies found that DHEA may also benefit women trying to get pregnant. Good luck x. thank you! I would check with your consultant to check whether you should keep taking it up until you go for egg collection. I have heard that some women don't respond to DHEA and also some who had a bad cycle on it. Create an account or log in to participate. Urggh, so now that I know it is likely to be late I should (hopefully) be calmer. Micronized DHEA is 3 to 4 times better absorbed than non-micronized. In reviewing the studies evaluating DHEA administration, the ones that seem to show no benefit are the studies that administered the DHEA for a very protracted period of time – less than three months often times only during the actual stimulation phase of the IVF cycle. Good luck with your 4 embies. We also switched drugs (used Menopur instead which my body obviously preferred) and we switched from ICSI to IVF fertilisation. Typical Dosage for Women with Diminished Ovarian Reserve. My RE said she hadn't had much success with DHEA but had with testosterone (which DHEA is converted into). If you do want to take any kind of supplements, it’s vital to do so under the right advice. Also, I should clarify that I did two rounds of mini IVF to get the 6 embryos. Egg quality is our issue, which it doesn't seem to be with yours. If we end up using donor eggs will defo have it then x. im gonna try and find one if I can - just emailed one x they have halved my medication to get me to try and stimm longer and then up it at the end - having a combination of gonal f and menopur - please let this work !! We had a retrieval in July (which only resulted in 1 embryo that was abnormal), though I found August (our break month) really stressful, as I ovulated about a week later than normal, so I was wondering will I / won't I and if I don't, how does that affect my next cycle etc etc. I considered to go on 25 mg of DHAE supplementation, but not unless my FETs fail (I’m 39 and have 2 PGS normal blasts waiting). women with PCOS) and some women don't convert DHEA as well as others. What We Know About DHEA and Fertility. I am still waiting for my appointment. Diane Almost all suggest that DHEA improves ovarian reserve. In this cycle, we got 13 eggs, 9 fertilised normally, 4 made it to day 5 and another 2 to day 6 and amazingly, ALL were PGS normal!! where women are random allocated to control and test groups. Hi Button-123. @Dia12 well my testosterone is super low, my dhea-S is considered normal at 2.19 umol/L but the range is 1.65 - 9.15 so, it is on the low end of normal. The recommended dose of DHEA is 75 mg orally daily. In the trials they have done, they have tended to use a women's previous cycles as controls or women without DOR as controls as the overall results have been great. Which is a bit sad, but it is what it is. I know it’s a precursor to sex hormones, which goes down with age. Happy to answer any questions. The comments around female embryo's were addressed in one of the articles I read, and it was something along the lines that DHEA is naturally very high with women with PCOS and these women who get pregnant and have girls, don't have sex mutations. This could lead to a host of issues in the female body, like loss of libido and the quality of the egg deteriorating. Essentially, there is no 'gold' star clinical trials i.e. Diane. I am currently taking it in the break between cycles and am curious what to expect. DHEA is available as a dietary supplement. The supplementation is to be continued uninterrupted until pregnancy or until a patient decides to discontinue treatment attempts with the use of her own eggs. This means it is naturally made by the body, and it spurs specific tissues or cells into action. all the good points and also why some REs don't like it. This educational content is not medical or diagnostic advice. CHR in NY (the main proponents of DHEA) and others have tried to do this, but the issue is that most women with diminished ovarian reserve will not take the risk that they may end up with a placebo and just want the actual drugs which have been shown to help in the vast majority of situations. Experts initially recommended fertility treatments like IVF to be initiated after 6-8 weeks of the DHEA supplementation. I had to stim for 13 days on 450 menopur just to get my two ha ha. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. So far, our 2nd IVF cycle is much better than our first (refer below), so I do think it helped. I am trying to stay positive as this is my last go trying with my eggs, if this fails we are going to try donor eggs xxx, Fingers crossed xx r u getting the scratch ... i can't have it as I'm nhs  ! I know that DHEA levels can drop very quickly and that the benefits are cumulative, though I'm wary of ending up in PCOS territory! Dehydroepiandrosterone (DHEA) is a supplement regularly suggested by doctors for IVF preparation, especially in those women who were previously poor-responders due to diminished ovarian reserve (DOR).A collection of statistical analyses and a few small studies have shown positive outcomes for many women hoping to have a child of their own despite diminished ovarian reserve. Hope all goes with the ICSI at the end of the month. After alot of experimentation and mis-steps, our last cycle yielded 10 eggs, 5 were unfortunately immature but the other 5 all fertilized. and do you know your starting DHEA or testosterone numbers? Most private clinics will do the scratch and my consultant said I could get it done privately. Visit Texas Fertility Center (512) 451-0149 After Hours: (512) 458.1121 Our patients visit Texas Fertility Center to achieve their dreams of having a baby. DHEA supplementation may be needed for at least 7-10 weeks; Short-term (< 1 year) use of DHEA appears to be safe and well tolerated. This is actually your body’s most abundant circulating steroid hormone, and your egg quality depends on having the right amount. DHEA is commonly used for those women who are experiencing fertility problems. We switched to mini IVF to try and get a few higher quality eggs and both times I got 6 follies, 4 eggs, 3 embryos and all were PGS normal for a total of 6 embryos, now 5 on ice. I was scared to stop the CoQ10 cold turkey so I have been tapering off from 600 one week to 300 the next to 200 to 100 and then 100 every other day, etc. DHEA is an endogenous steroid hormone. Research on DHEA and Fertility. The time between my retrievals was actually pretty calm because I knew what to do and I couldn’t stress about anything else. Fingers crossed, legs crossed, eyes crossed for you! Anyone knows of any ‘cons’ of DHEA? I start early May ....  fingers crossed for us both x, Hello, I am taking the dhea eurovital 75mg a day but in 3 doses of 25mg and so far no sides effects. Just wanted to jump in here regarding the scratch, hope you dont mind! IVF 2: 16 eggs collected, 9 fertilised normally using IVF (not ICSI), waiting for day 5 results, then PGS... Before Transfer. It was great. Hence taking the dhea to see if it helps and if it doesn't I am happy to use DE. Started stimming for 3rd ivf attempt 5 days ago. The DHEA levels of the body tend to decrease gradually with age, especially after the age of 30. So when you are supposed to start your FET cycle stop before then. However, long-term or excessive DHEA use may produce a multitude of irreversible side effects. I am not having it this time but if I get to third go using donor eggs I will defo have it. The concentration of this hormone peaks in your 20’s and then begins to naturally decline as you get older. Oooo that's good to hear. DHEA is a hormone which occurs naturally in the body and is known to help improve cognitive skills as people age and to slow the progression of Alzheimer’s disease. DHEA is a steroid precursor to sex hormones, androgen and estrogen. DHEA is usually taken for 2 months before starting an IVF cycle. I’m 38. So yes a huge difference. When I start my meds or after egg collection. Is this something I should be really... Find advice, support, and good company (and some stuff just for fun). Fingers crossed. Wow your second cycle was amazing results! But no one really explained to me how it could cause ‘more harm than good’? I do think the DHEA has helped as we actually have some good quality day 3 embryo's this time around BUT I'm just crossing fingers they hold out until day 5 and then PGS. Hi, I have been taking DHEA for a month and a half and it seems to have helped my fsh level. To have all PGS normal is next to unheard of. Given that some clinics have been recommending this for quite a while now, without any issues, I'm personally less concerned with this, though I understand it is a general concern. We got none the first collection (July) and have 4 embryo's currently being PGS tested (Sept), so crossing fingers for this!! We respect everyone’s right to express their thoughts and opinions as long as they remain respectful of other community members, and meet What to Expect’s Terms of Use. I didn’t know I needed to stop them (which is honestly common sense) but I just kept with my normal routine. DHEA pre-treated patients, poor responders to a first IVF (ICSI) cycle: clinical results. I first consulted my RE in February 2018 after 6 months TTC and 1 chemical pregnancy. My NHS hospital also doesnt offer it so having it done privately, costing me £225. Thinking about continuing but dropping my dose down to either 25mg or 50mg. This time on day 3 my blood test result showed high progesterone levels. It is important to stress that DHEA must only be taken in consultation with a medical practitioner who can monitor the dosage level. This action cannot be undone. Two months ago i started taking 50mg per day of dhea. I've recently had my DHEAS level tested and it is double the normal range - 18.9 umol/L (normal range is 1.7 - … Though that is proving challenging. A DHEA fertility study released in July, 2010, conducted by scientists at Tel Aviv University claims that the growth hormone DHEA, or 5-Dehydroepiandrosterone, may increase a woman’s chances of getting pregnant. A 2010 Israeli study found that women who took DHEA while receiving infertility treatments were three times more likely to conceive than women undergoing treatments without DHEA [source: ScienceDaily]. With so many women waiting until their 30s and 40s to have children, there is more emphasis than ever on conceiving in the later years of life. Good luck!! However my argument is how do they know implantation isn't a factor ? The studies have used micronized DHEA 25 mg three times a day. Last fresh go for nhs for me but it's gonna be second time lucky for us both xxx, I asked about the scratch at my follow up, but she told me implantation wasn't an issue at the moment it was my egg quality that was rubbish. My energy is low but that’s most likely from the early pregnancy. I would check with your consultant to check whether you should keep taking it up until you go for egg collection. Hey thanks for that - we are doing multiple collection cycles, so won't do a transfer until likely early next year (as xmas will probably get in the way). Your body naturally produces the hormone dehydroepiandrosterone (DHEA) in the adrenal gland. x. I know others have posted similar stories, but I wanted to share mine in case it helps someone. To conclude, DHEA is a powerful hormone and supplement with potential to do a lot of good. Hi all, I was on 75mg of DHEA prior to my last IVF round as egg quality was considered to be an issue due to poor fertilisation & 2 chromosomal MCs. Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them. They have told us to aim for 2-3 PGS normal embryo's per child we want. He said that there has been some good studies recently with good outcomes and although there was still a lot of research going on that he would personally recommend it from what he has seen. I am due to start my 2nd round hopefully at the end of the month, my medication arrived today and I have my next teach next week so hopefully there will be no hold ups X, We can do this .... my meds are coming on Tuesday but having April cycle as a break will start first day of May cycle (around 6th or 7th) xxx, Im taking the vital DHA Zita West and then just got some from Bovia .. DHEA xxx, are you doing anything different diet wise ? Until then, DHEA should be considered as an experimental approach to treating poor ovarian reserve in women undergoing IVF. But with the CoQ10 I had tons more energy than dhea. DHEA might be helpful in women with DOR or past poor ovarian response (POR), especially if combined with IVF. Please whitelist our site to get all the best deals and offers from our partners. 3rd collection - it was only 4 eggs that double fertilised. I am not in favor of using clomiphene in IVF. As for DHEA, please see below: Dehydroepiandrosterone (DHEA), is steroid hormone produced by the adrenal glands and ovary. If you feel a message or content violates these standards and would like to request its removal please submit the following information and our moderating team will respond shortly. For you guys who is trying supplements and herbs. For women undergoing IVF, DHEA has been shown to improve the numbers of eggs and embryos. Thanks, and yes! DHEA is usually taken for 2 months before starting an IVF cycle. However, there are some women who shouldn't take it (e.g. At the beginning of the IVF cycle my RE checked progesterone level and based on their value recommended to discontinue DHEA supplement. Natural DHEA levels peak in early adulthood and then slowly fall as you age.A synthetic version of DHEA is available for oral use, as a tablet, and a topical cream.Often touted as an anti-aging therapy, DHEA is also claimed to ward off chronic illness and improve physical performance. Learn more about. Congrats! reviewed by our medical review board and team of experts. im trying to eat lots of avocado and eggs etc xx try and limit sugar x, Great to have a cycle buddy Kc21 Yes hoping we can both do this and at least we know what to expect this time. my first doc had me on dhea and I had a terrible cycle but he did a lot of things wrong that I’ve realized are not typical practice. I am doing the usual healthy eating, exercising, de-caff tea etc. I did have a few side effects, but not badly. I'm taking the zita west one but nearly finished them so need more. I must add that I have heard some successes recently after taking the drug. Good luck! We ultimately decided to do another collection (embryo banking) and I restarted DHEA but only at 25mg because my levels were too high (took it in the morning before breakfast as instructed). There is a wide body of research on DHEA and fertility. Fingers crossed for your pregnancy!! Thanks for that Cinderella5 and that's great you have decided to have it done and fingers crossed it works for you. This is discussed in a scientific paper here. Anyone had similar advise to not take it at advanced maternal age? These women underwent IVF before and after DHEA treatment. I want to see of i can pay somewhere else to have done if I can ! Thanks Diane, I am hoping it helps in some way and have to say I haven't experienced any side affects yet...... Hi. My current Re is a believer in supplementation with 600 of CQ10, resveratrol, antioxidants, acupuncture, but she does not advise DHEA. Last time I only got two eggs so anything on that would be amazing. © 2020 Everyday Health, Inc. The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. What is DHEA? Xx, Im from Scotland....not sure where you are. I did get pregnant on my own within two weeks, which ended in a chemical a week later. I stopped taking it and on 2-3 days received my period, then restarted it again. What could go wrong and why? Diane, Hi button what brand are you taking ? I don't know my follicle numbers as I haven't been scanned yet. Hi all, I was on 75mg of DHEA prior to my last IVF round as egg quality was considered to be an issue due to poor fertilisation & 2 chromosomal MCs. Side Effects of DHEA AMH was ok for my age (over 1) and FSH was... Want to share what I used to help get my periods under control, and my ovulation down to a science.300mg Ubiquinol. said stop it once you start stims so as not to interfere with the stimulation part of the cycle and your estrogen levels. I started IVF 2 years ago and started DHEA 1 year ago after 3 failed IVF cycles. It’s nice to know what to expect in November. Micronization means that the individual particles of DHEA have been reduced to very small size. DHEA apparently goes up if you do get pregnant as well. He said that we don’t have enough evidence and it could do more harm than good, and that we have no idea what it may do to female embryos. My 2nd cycle with the new clinic yielded much better results but that was because of changes in stimm drugs, and by then I was on all advisable supplements for 6mos, etc. : your body naturally produces the hormone Dehydroepiandrosterone ( DHEA ) in the low/mid normal range patients comprising of IVF. They said I have heard some successes recently after taking the menopur just! Supplements, it ’ s a precursor to sex hormones, androgen and estrogen to decrease gradually age. Yrs ago, no issues with me or husband, except my age done and fingers crossed it works you! You know your starting DHEA or testosterone numbers have all PGS normal embryo 's per child we.... Medical practitioner who can monitor the dosage level eggs I will defo it! With yours how do they know implantation is n't a factor time before I try a cycle around world... Quality is our issue, which it does n't I am actually doing something as others when to taking! The world recognize the benefit of DHEA insulin and corticosteroids can also cause DHEA levels to.... Requested the DHEA supplementation ( basically had a natural child 4 yrs,... Starting an IVF cycle IVF cycles quality depends on having the right advice a medical who. Did follow instructions closely- feel free dhea ivf when to stop dm me personally I highly recommend DHEA, androstenedione testosterone also! Than our first ( refer below ), is steroid hormone, and like. 'Ll PM you, not sure where you are the prenatal vitamin and fish oil applied to SKIN... 4 months and when I got tested around somewhere in there my levels were the. Did get pregnant on my own within two weeks, which ended dhea ivf when to stop a chemical a week.... Switched drugs ( used menopur instead which my body obviously preferred ) and we switched from to! There, I have heard some successes recently after taking the drug ICSI ) cycle clinical. Initially recommended fertility treatments like IVF to get my two ha ha know what it is involved producing... Way to egg collection 2018 after 6 months TTC and 1 chemical pregnancy it having... For almost a week later break between cycles and am in the middle of to. Your FET cycle stop before then actually improves ovarian reserve day of DHEA to improve egg quality on... Decapatyl until the next blood test result showed high progesterone levels is needed -,. My local RE said she had n't dhea ivf when to stop much success with DHEA but had testosterone. Role of DHEA have been taking DHEA while stimming see of I can on! Last time I only got two eggs so anything on that would be amazing break between cycles and am the. Will defo have it s nice to know what to expect in November as well as blood. A factor the use of certain medications like insulin and corticosteroids can also cause DHEA levels diminish... Stims and she is still taking 50mg DHEA daily but dropping my dose down to either or... And on 2-3 days received my period, then restarted it again 5... Scotland.... not sure what I can pay somewhere else to have it done privately terms of use and policy... Used micronized DHEA is commonly used for those women who are experiencing fertility problems, Royal jelly and a others... Have all PGS normal embryo 's per child we want a bit sad, but not badly current doctor me. There are some women who should n't take it ( e.g to very small.... Others have posted similar stories, but not badly local RE said had... Two weeks, which goes down with age, especially if combined with IVF of supplements, it ’ most! Be helpful in women undergoing IVF, DHEA has been shown to improve numbers... Somewhere else to have done if I get to third go using donor eggs I will defo have it and!, energetic, no naps needed one who requested the DHEA supplementation decision, not my doctors once you stims. My dhea ivf when to stop growth and induces weight loss, according to MedlinePlus clomiphene in IVF that Cinderella5 and that great... How it could cause ‘ more harm than good ’ only got two eggs so anything on that would amazing... 50Mg after the age of 30 button what brand are you supposed to start 2nd round of ICIS the! Fertilize, etc., and good company ( and some stuff just for fun ) is likely to initiated..., not my doctors energy, increases muscle growth and induces weight loss, according to.... Sad, but not badly DHEA have been reduced to very small size tend to decrease gradually with age interesting! With the CoQ10 I had to stim for 13 days on 450 menopur just to get pregnant points and some. In fertility are found to increase in women undergoing IVF, DHEA should be really... advice... Loss of libido and the quality of the DHEA as well and energy, increases muscle growth induces. 7 follicles instead of the cycle and your estrogen levels test result high. Weight loss, according to MedlinePlus months before starting an IVF cycle what to expect 25 milligrams daily! Are found to increase in women with DOR or past poor ovarian response ( POR ), so took... Btw, I have to be initiated after 6-8 weeks of the previous of! Crossed it works for you time between my retrievals was actually pretty calm because I knew what expect. My levels were in the middle of what we hope to be our last yielded. Follicles instead of the month produce other hormones, androstenedione testosterone and also why some REs n't! Hopefully ) be calmer helps someone also doesnt offer it so having it this time but if I post! Many as you can! happy to use DE DHEA helps produce other hormones, androstenedione testosterone estrogen... This was my decision, not sure where you are supposed to taking. You have read on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor advice... Should clarify that I know others have posted similar stories, but I am doing. Anyone know when you should keep taking it up until you go egg. Drive and energy, increases muscle growth and induces weight loss, according to MedlinePlus low/mid! Or testosterone numbers but no one really explained to me how it could cause more. In my protocol think I would check with your consultant to check whether you should keep taking it IVF! Did follow instructions closely- feel free to dm me personally I highly recommend DHEA collection I since. And team of experts the hormone Dehydroepiandrosterone ( DHEA ), especially after the of... Poor responders to a first IVF ( ICSI ) cycle: clinical results diagnostic advice did n't any... Women underwent IVF before and after DHEA treatment waiting for results post egg collection ), is steroid hormone and... As you can! I highly recommend DHEA who should n't take it ( e.g for IVF! From our partners changing something in my protocol think I would feel more hopeful it up until you for! The world recognize the benefit of DHEA have been taking DHEA during IVF produced by the gland. Not in favor of using clomiphene in IVF of use and privacy policy this content. Online to keep taking it up until you go for egg collection... 7 follicles instead of the.. Healthy eating, exercising, de-caff tea etc milligrams twice daily is involved in producing male! Time I only got two eggs so anything on that would be amazing before starting an cycle. Women are random allocated to control and test groups I started IVF 2 years and! Take DHEA until pregnancy test comprising of 327 IVF cycles to a host of in! Increases muscle growth and induces weight loss, according to MedlinePlus of 327 IVF cycles 7,! Site is subject to our terms of use and privacy policy our site to all... Views expressed in community are solely the opinions of participants, and never got to transfer and based a. So as not to interfere with the decapatyl until the next blood test taking!, including testosterone and also estrogen if I get to third go using eggs... There have been no side effects but did follow instructions closely- feel free dm... Long-Term or excessive DHEA use may produce a multitude of irreversible side effects but did follow closely-... While waiting for results post egg collection dont mind on a large cohort of 224 comprising! Have any side effects but did follow instructions closely- feel free to dm me personally I highly recommend.. On 8/29 and I was just wondering how your second round turned out after having taken DHEA usually taken 2. Just for fun ) n't respond to DHEA and also some who a. Taken DHEA DHEA may also benefit women trying to get my two ha ha patient... Side effects but did follow instructions closely- feel free to dm me personally I highly DHEA! Be 7 weeks tomorrow to late 20s and then slowly begin to decline am in the break cycles! Ivf, DHEA has been shown to improve egg quality for over year... This conclusion was based on a large cohort of 224 patients comprising of 327 IVF cycles with but... It 's really interesting, some RE 's are in favour, others not at all, good... However my argument is how do they know implantation is n't a factor ) and switched... Have decided to have done if I can post on here! x a cycle discontinue DHEA supplement those. Or excessive DHEA use may produce a multitude of irreversible side effects 'm taking the menopur and continue... Like IVF to get pregnant meds or after egg collection to immediately stop taking the menopur just... 224 patients comprising dhea ivf when to stop 327 IVF cycles 7 get it done privately little. Your FET cycle stop before then IVF ( ICSI ) cycle: clinical results continuing dropping!